Welcome to the November 2008 Cell Migration Update, your one-stop resource for news, highlights and research on cell migration.
FEATURED ARTICLES
Specially written Editor's reviews of the hottest new articles
Myosin-II: An extending tail
Standfirst
Whereas myosin-IIA forms actin cables in regions of protrusion, myosin IIB is confined to the rear where its activation induces the formation of an extended tail that supports directional migration.
Original research paper: J Cell Biol. 183, 543-554 (2008)
Adhesion dynamics: Actin and microtubules get along with ACF7
Standfirst
The microtubule-actin crosslinking protein ACF7 coordinates microtubule growth along filamentous actin towards focal adhesions (FAs). Microtubule targeting to FAs is required for FA turnover and cell migration.
Original research paper: Cell 135, 137-148 (2008)
RESEARCH HIGHLIGHTS
Synopses of important recent articles
Membrane trafficking: Recycling integrins
Standfirst
Two studies now provide insights into the regulation of integrin trafficking by the Rab family of small GTPases in both cell migration and cytokinesis.
Nature Reviews Molecular Cell Biology 9, 826 - 827 (2008)
Metastasis: Preparing the soil
Standfirst
A new pathway involving Toll-like receptor 4 has been shown to enhance metastasis to the lungs by promoting the accumulation of macrophages and haematopoietic progenitors.
Nature Reviews Cancer 8, 832 - 833 (2008)
NEWS
The latest news selected from the CMC, Nature News and journals from the Nature family
Integrin structure: Let's get activated.
No more third time lucky
Standfirst
NIH clamps down on proposal resubmissions.
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CONSORTIUM ACTIVITIES
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